Drying Using Supercritical Fluid Technology as a Potential Method for Preparation of Chitosan Aerogel Microparticles

Preparation of Chitosan-Based Hemostatic Sponges by Supercritical Fluid Technology

Using ammonium bicarbonate (AB) particles as a porogen, chitosan (CS)-based hemostatic porous sponges were prepared in supercritical carbon dioxide due to its low viscosity, small surface tension, and good compatibility with organic solvent. Fourier transform infrared spectroscopy (FTIR) spectra demonstrated that the chemical compositions of CS and poly-(methyl vinyl ether-co-maleic anhydride) ...

Application of Supercritical Fluid ‎Technology for Preparation of Drug Loaded ‎Solid Lipid Nanoparticles

   Small changes in pressure or temperature, close to the critical point, lead to large changes in solubility of supercritical carbon dioxide (CO2). Environmentally friendly supercritical CO2 is the most popular and inexpensive solvent which has been used for preparation of nanodrugs and nanocarriers in drug delivery system with supercritical fluid technology. Delivery...

Preparation of Pharmaceutical Powders using Supercritical Fluid Technology

Production of Spherical Aerogel Microparticles by Supercritical Extraction of Emulsion

Due to high surface area, low density, open pore structure and excellent insulation properties aerogels were intensively investigated in the past decades for diverse range of applications. The state of the art of aerogel production by supercritical drying is to produce monolithic aerogel, where the sol is aged in molds and dried by extraction with supercritical CO2. Aerogels in form of spherica...

Preparation of controlled release microspheres using supercritical fluid technology for delivery of anti-inflammatory drugs.

Ethylcellulose/methylcellulose blends were produced using different precipitation techniques and impregnated with naproxen, a non-steroidal anti-inflammatory drug (NSAID). Solvent-evaporation technique was used not only for the preparation of ethylcellulose/methylcellulose microspheres but also to encapsulate naproxen. Supercritical fluid (SCF) impregnation was also performed to prepare naproxe...